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High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2.

Identifieur interne : 000593 ( 2020/Analysis ); précédent : 000592; suivant : 000594

High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2.

Auteurs : Steven Sanche ; Yen Ting Lin ; Chonggang Xu ; Ethan Romero-Severson ; Nick Hengartner ; Ruian Ke

Source :

RBID : pubmed:32255761

Abstract

Severe acute respiratory syndrome coronavirus 2 is the causative agent of the 2019 novel coronavirus disease pandemic. Initial estimates of the early dynamics of the outbreak in Wuhan, China, suggested a doubling time of the number of infected persons of 6-7 days and a basic reproductive number (R0) of 2.2-2.7. We collected extensive individual case reports across China and estimated key epidemiologic parameters, including the incubation period. We then designed 2 mathematical modeling approaches to infer the outbreak dynamics in Wuhan by using high-resolution domestic travel and infection data. Results show that the doubling time early in the epidemic in Wuhan was 2.3-3.3 days. Assuming a serial interval of 6-9 days, we calculated a median R0 value of 5.7 (95% CI 3.8-8.9). We further show that active surveillance, contact tracing, quarantine, and early strong social distancing efforts are needed to stop transmission of the virus.

DOI: 10.3201/eid2607.200282
PubMed: 32255761


Affiliations:


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pubmed:32255761

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{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    2020
   |étape=   Analysis
   |type=    RBID
   |clé=     pubmed:32255761
   |texte=   High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2.
}}

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